What’s the difference between a food allergy and a food intolerance (or adverse reaction to food)?
Although they can look similar, food allergies and adverse food reactions are very different. It is important for parents to understand the difference.
A food allergy happens when your child’s immune system mistakes a food protein for something harmful and reacts to it. Even a very small amount of the food can trigger symptoms, and reactions can be serious. Allergic reactions can sometimes lead to anaphylaxis, a severe reaction that can affect breathing, blood pressure, and consciousness. This is a medical emergency.
An adverse reaction to foods, or food intolerance, does not involve the immune system. Instead, it usually happens when your child’s body has trouble digesting a certain food. They may cause tummy pain, bloating, wind, or diarrhoea, but they do not cause anaphylaxis. In short, intolerances can be uncomfortable, but they are not life-threatening.
If you’re unsure whether your child has a food allergy or adverse reactions to food, getting the right diagnosis can bring clarity and peace of mind.
IgE and non-IgE mediated food allergies – what’s the difference?
Not all food allergies behave in the same way. Broadly, they are divided into IgE-mediated and non-IgE–mediated food allergies.
IgE-mediated food allergies are the “classic” food allergies that most people think of. Reactions usually happen within minutes to 1–2 hours of eating the food and can include:
- Hives or swelling
- Vomiting
- Wheezing or breathing difficulties
- Anaphylaxis
These allergies can often be supported by blood tests or skin prick tests, alongside a careful clinical history.
Non-IgE–mediated food allergies cause delayed reactions, typically 2–24 hours after eating the food. Symptoms most often affect:
- The gut – abdominal pain, diarrhoea, vomiting, reflux, feeding difficulties
- The skin – eczema flares
They can sometimes cause other, less specific symptoms as well. Importantly, blood tests and skin prick tests are not helpful for diagnosing non-IgE–mediated allergies.
Instead, diagnosis is based on a structured elimination and reintroduction process. The suspected food is excluded for 4 weeks, then reintroduced for 4 weeks. If symptoms improve during exclusion and then return on reintroduction, a non-IgE–mediated food allergy is diagnosed.
Understanding whether your child’s allergy is IgE or non-IgE mediated is crucial, as it affects how reactions present, how they are investigated, and how they are managed day to day.
How common are food allergies in children?
Food allergies affect around 1 in 10 children, with higher rates in infants and young children. The most common triggers include milk, egg, peanut, tree nuts, wheat, soy, and seafood.